نوع مقاله: تالیفی
نویسنده
پژوهشگاه علوم و فنون هسته ای
چکیده
کلیدواژهها
موضوعات
عنوان مقاله [English]
نویسنده [English]
Hydrogels are cross-linked three-dimensional networks that are capable of absorbing large amounts of water without being dissolved. Hydrogels can be prepared by crosslinking of either natural or synthetic polymers. Recently, interests in preparation and biomedical applications of the hydrogels prepare dusing natural polymers have grown intensively due to their excellent biocompatibility, biodegradability, biofunctionality and other desirable properties. Until now, several chemical and physical crosslinking methods have been studied to achieve hydrogels from natural polymers. Among chemical crosslinking methods, ionizing irradiation presents several advantages as it may occur without the need to add chemical initiators/crosslinking agent with subsequent separation of side reaction products, and the final products can be sterilized simultaneously during hydrogel formation. Usually, ionizing irradiation of a few natural polymers causes the chain scission reaction with consequent formation of lower molecular weight fragments. In recent years, several researchers have focused on the development of new methods to prepare hydrogels from natural polymers by ionizing irradiation. Some of these methods are irradiation at paste-like state, irradiation of polymers bearing carboxylic acid groups at acidic media, irradiation in presence of alkyne gas and chemical grafting with vinyl compounds.
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