عنوان مقاله [English]
نویسندگان [English]چکیده [English]
Oral route is the most preferred route by medical practitioners and manufacturer due
to patient's acceptability. Fast dissolving tablets have been developed because of low
bioavailability and weak acceptability of pediatric and geriatric patients who experience
difficulties in swallowing the traditional oral solid-dosage forms. As a result of low
bioavailability of fast dissolving tablets, oral thin films have been developed. These films
are the most advanced form of oral solid dosages due to more flexibility and comfort and
include a polymer, an active ingredient, flavoring and coloring agents, and surfactants.
Oral thin films are made mostly with solvent casting and hot melt extrusion. Oral strips are
evaluated for various attributes such as thickness, disintegration and dissolution study and
mechanical properties. These films have many applications such as taste masking, fast and
sustainable drugs release. At the moment, film formulations with encapsulated drugs are
commercially launched using the oral film technology. It is predicted that the value of the
overall oral thin film market will grow significantly.