Application of Three-Dimensional Polymers as Drug Carriers

Document Type : compile

Authors

عضو هیات علمی

Abstract

In recent years, designing novel drug delivery systems using new technologies such as nano as well as nano-drug synthesis for treatment of various disease has been considered from researchers' point of view. The main goal of these novel designed systems is decreasing the side effects of drugs by controlling the applied dosage and releasing of drugs at the subject point. To do so, different drug carriers with the unique properties have been suggested. Nanoparticles are one of the most important carriers in this field. To improve the bonding of the drugs to the outer surface of these nanoparticles, biodegradable and biocompatible polymers with low toxicity can be used. These biodegradable polymers have been used frequently as drug delivery vehicles due to their grand bioavailability, better encapsulation, to increase the chemical stability, control release and less toxic properties. However, these polymers should have special structural, physical and chemical properties. This review is an introduction to these polymers which apply in drug delivery systems by a particular attention on three-dimensional polymers such as dendrimers, hyper-branched and star polymers.

Keywords