High chemical activity materials (HCAMs) pose significant safety challenges due to their high mechanical and thermal sensitivity. Polymeric materials due to their viscoelastic behavior are one of the interesting choices and fluoroelastomer have suitable properties for this function. Coating these materials with fluoroelastomers is one of the most effective strategies to reduce sensitivity, enhance thermal stability, and improve chemical activity performance. Fluoroelastomers are broadly classified into organic types, including FKM, FFKM, and FEPM, and inorganic types, such as fluorosilicones and fluorophosphazenes. The exceptionally strong C–F bond (~485kJ/mol) provides excellent thermal and chemical stability, outstanding resistance to oxidation, fuels, and solvents, and compatibility with nitramine compounds. These properties make them ideal binders and coatings for polymer bonded high chemical activity materials (PBHCAMs). Primary coating methods including aqueous suspension, spray drying and electro spraying enable the fabrication of uniform core–shell structures with controlled morphology. Studies confirm that these coatings improve decomposition temperatures while preserving energy density and chemical reaction rates. Overall, fluoroelastomers coating offers an efficient, cost-effective, and tunable strategy to achieve enhanced safety alongside optimal performance, establishing a foundation for designing safer, more stable, and reliable next-generation high-energy systems.